Advances in the management of asymptomatic hyperparathyroidism
نویسنده
چکیده
Asymptomatic primary hyperparathyroidism (PHPT), a condition defined as hyperparathyroidism that lacks specific symptoms or signs and with calcium levels of less than 1 mg/dL above the upper limit of normal, is a common clinical problem. Two previous conferences on the management of asymptomatic PHPT (a Consensus Development Conference and a National Institutes of Health workshop) indicated that medical monitoring rather than surgery is appropriate in certain patients with this condition. The Third International Workshop on the management of PHPT reviewed evidence that has become available since the last workshop in 2002. The purpose of this report is to describe recent advances reviewed during the third workshop on asymptomatic PHPT held in 2008.
منابع مشابه
Primary hyperparathyroidism: diagnosis and management in 2017.
Primary hyperparathyroidism is a relatively common endocrine condition, which is being increasingly identified in its asymptomatic stage, following routine evaluation of serum calcium levels. Parathyroid hormone and calcium excess impact multiple organ systems. The greatest effects are seen on the skeleton and the kidney. This overview describes the current advances in the diagnosis, presentati...
متن کاملMedical management of asymptomatic primary hyperparathyroidism: proceedings of the third international workshop.
BACKGROUND Primary hyperparathyroidism (PHPT) is a common endocrine disorder that is frequently asymptomatic. The 2002 International Workshop on Asymptomatic PHPT addressed medical management of asymptomatic PHPT and summarized the data on nonsurgical approaches to this disease. At the Third International Workshop on Asymptomatic PHPT held in May 2008, this subject was reviewed again in light o...
متن کاملThe surgical management of asymptomatic primary hyperparathyroidism: proceedings of the Fourth International Workshop.
OBJECTIVE The surgical management of primary hyperparathyroidism (PHPT) has undergone considerable advances over the past two decades. The purpose of this report is to review these advances. PARTICIPANTS This subgroup was constituted by the Steering Committee of the Fourth International Workshop on the Management of Asymptomatic Primary Hyperparathyroidism to address key questions related to ...
متن کاملA pilot study to examine the management of asymptomatic hyperparathyroidism in Japanese patients in accordance with the guidelines for asymptomatic PHPT proposed at the Third International Workshop in 2008.
Objective The treatment for asymptomatic primary hyperparathyroidism (PHPT) remains controversial. In 2008, the Third International Workshop on the Management of Asymptomatic PHPT proposed a set of guidelines for the management of asymptomatic PHPT. We therefore evaluated the application of the Workshop recommendations in Japanese patients with asymptomatic PHPT. Methods We analyzed each parame...
متن کاملPrimary Hyperparathyroidism in Patients with Multiple Endocrine Neoplasia Type 1
Primary hyperparathyroidism may occur as a part of an inherited syndrome in a combination with pancreatic endocrine tumours and/or pituitary adenoma, which is classified as Multiple Endocrine Neoplasia type 1 (MEN-1). This syndrome is caused by a germline mutation in MEN-1 gene encoding a tumour-suppressor protein, menin. Primary hyperparathyroidism is the most frequent clinical presentation of...
متن کامل